Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair.

J Neuroinflammation · 2020 · PMC7488082 · PMID 32907600

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did not reach statistical significanceno p-value reported

Therefore, subsequently to the adhesion, we examined the transmigration of PBMCs through the in vitro BBB model and revealed a dose-dependent increase in PBMCs transmigration starting with a 2.7 ± 1.1 fold increase at 400 μM PX (which did not reach statistical significance) and 12.9 ± 1.1 fold increase at 600 μM PX (Fig. 1 g).

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