Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells.

Subanalysis of the population that received DC vaccines ( n = 8) suggested a trend toward expansion of the CD8 + T cell population (and further reduction of CD4:8) compared with those receiving LEN/DEX therapy ( n = 13) at the post-ASCT time point; however, this did not reach statistical significance and was indistinguishable by EOT ( Supplementary Figure 1 ).

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