Helminth-Induced and Th2-Dependent Alterations of the Gut Microbiota Attenuate Obesity Caused by High-Fat Diet.

A clear trend of increased mRNA expression of GPR41 , GPR43 , and GPR109 was detected in the colon ( Figure 6 A–C ) and liver ( Figure 6 G–I ) of HFD-fed mice with helminth infection (HFD- Hp ), and also in the colon ( Figure 6 D–F ) and liver ( Figure 6 J–L ) of the recipients of H polygyrus –altered microbiota (HFD+ Hp -F) compared with their corresponding control animals.

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