Suppression of <i>spastin</i> Mutant Phenotypes by <i>Pak3</i> Loss Implicates a Role for Reactive Glia in AD-HSP.

Terminal bouton number in spastin 5.75 mutants also decreased to wild type levels, although due to difficulties obtaining healthy e22c,sqh; spas paired controls (i.e., animals with the e22c,sqh-GAL4 driver and spastin mutation but no Pak3 R NAi ), this change did not reach statistical significance ( Figure 2J ; p = 0.13 for e22c,sqh; spas vs. e22c,sqh > Pak3 R NAi , spas ).

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