Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction.

However, in the multivariate analysis to determine the independent variables of peak VO 2 after division of the non-reduced LVEF cohort into the preserved LVEF (≥ 50%) and the mid-range LVEF (40–49%) cohorts, the presence of T2DM did not reach statistical significance in the CHF patients with preserved LVEF, which is inconsistent with a previous study [ 11 ].

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