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Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation.

Front Physiol · 2020 · PMC7506137 · PMID 33013477

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showed a trendno p-value reported
A dose-dependent increase in heart rate was observed, which showed a trend to return to baseline within the time of measurement.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.