Vitamin D supplementation and serum neurofilament light chain in interferon-beta-1b-treated MS patients.

Brain Behav · 2020 · PMC7507359 · PMID 32705821

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

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boldest claim

The sentences

a nonsignificant trendp = .09so close (0.05 < p ≤ 0.1)

At the study baseline, there was a nonsignificant trend for a positive correlation of sNfL and serum 25(OH)D ( r = .30, p = .09), but at month 12 no correlation could be seen ( r = −.001, p = .99).

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showed a trendno p-value reported

Neither of these studies supported and effect of vitamin D on sNfL, but among the Dutch participants of the SOLARIUM study, higher week 48 NfL levels showed a trend for a higher risk of combined unique active lesions in brain MRI (Smolders et al., 2020 ).

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