Barely Significant
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Risk to human health related to the presence of perfluoroalkyl substances in food.

EFSA J · 2020 · PMC7507523 · PMID 32994824

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an increasing trendno p-value reported
( 2010 ) reported on the occurrence of PFTeDA in Peregrine falcon ( Falco peregrinus ) eggs from 1974 to 2007 and identified an increasing trend up to 2004.

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For Hib the modelling of the dose response did not reach statistical significance for the sum of the 4 PFASs.

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a decreasing trendno p-value reported
PFNA; concentrations in biota generally show an increasing trend (21 studies) or no significant trend (19 studies), whereas one study on Beluga Whales ( Delphinapterus leucas ) showed a decreasing trend.

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borderline significantno p-value reported
PFOS was not associated with SGA [OR: 0.82 (95%CI: 0.74, 0.91) per interquartile range increase in exposure] while the corresponding estimate for PFOA showed a borderline significant increased risk of SGA [OR: 1.64 (95%CI: 0.97, 2.76)].

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a positive trendno p-value reported
There was also a positive trend for PFNA when calculating odds ratios of having levels of ALT higher than the 75th percentile of levels in the NHANES surveys.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.