BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation.

Cell Rep · 2020 · PMC7507985 · PMID 32966794

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did not reach statistical significanceno p-value reported

However, after siRNA knockdown of Top2α or Top2β for 48 h in HeLa cells, we observed an effect on the DNA damage caused by 6 h of dBET6 inhibition that did not reach statistical significance ( Figures S4 F and S4G).

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