showed a trendp=0.225
page 10 “In the model with mortality as outcome, week-2-MP patients showed a trend for lower mortality (HR 0.48, 95%CI 0.14 to 1.57, p=0.225), whilst out-of-week-2- MP patients had an increased risk of death (HR 2.49, 95%CI 0.87 to 7.11, p= 0.088), both compared with no MP patients.“ Comparison among 2-week-MP, out-of-week-2-MP and no MP patients is critical for this study.