Targeted Sequencing of Sorted Esophageal Adenocarcinoma Cells Unveils Known and Novel Mutations in the Separated Subpopulations.

Although Kaplan-Meier analysis did not reach statistical significance for cancer-specific and disease-free survival (logrank P = 0.383 and P = 0.211, respectively), the survival patterns were different for patients with SMAD4 loss vs normal SMAD4 expression (5-year cancer-specific survival 25.1% vs 62.5%; 5-year disease-free survival 22.9% vs 62.5%).

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