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The Relationship of Coronary Artery Calcium and Clinical Coronary Artery Disease with Cognitive Function: A Systematic Review and Meta-Analysis.

J Atheroscler Thromb · 2020 · PMC7508729 · PMID 32062643

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The Rotterdam study in the elderly ( n = 2,326) showed that increased CAC volume was associated with modestly increased risk of dementia after 6 years of follow-up 18 ) , but this result did not reach statistical significance (HR 1.05 per Ln(calcium volume+1.0 mm 3 ), 95%CI 0.80–1.36).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.