Association of the <i>RPA3-UMAD1</i> locus with interstitial lung diseases complicated with rheumatoid arthritis in Japanese.

In the large-scale GWAS of Japanese, rs12702634-C demonstrated nominally significant increased risk of ILD in general populations (OR=1.25, 95% CI 1.05 to 1.49, p=0.013; online supplementary table 7 ). 17 No association with any smoking behaviours was observed (p>0.18). 18 The RA-ILD risk variant of rs12702634 was located in the intron region of RPA3 and UMAD1 ( figure 1B ).

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