There was a clear trend showing a negative correlation between p16 + epithelial cells and UWS in pSS patients, but without statistical significance ( r = –0.31, P = 0.0665, Fig. 2A ). p16 + BSD cells and UWS in these patients showed significant and stronger correlation ( r =–0.52, P = 0.0014, Fig. 2B ).
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Progenitor cell niche senescence reflects pathology of the parotid salivary gland in primary Sjögren's syndrome.
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