Association of iron deficiency, anaemia, and functional outcomes in patients undergoing edge-to-edge mitral valve repair.

ESC Heart Fail · 2020 · PMC7524056 · PMID 32621385

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0900

boldest claim

The sentences

borderline significantP = 0.06so close (0.05 < p ≤ 0.1)

Anaemia showed a borderline significant association with mortality (HR: 2.2; 95% CI: 0.96–5.08; P = 0.06) and a significantly increased risk of heart failure hospitalization (HR: 3.28; 95% CI: 1.06–10.19; P = 0.04).

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showed a trendP = 0.09so close (0.05 < p ≤ 0.1)

Anaemia was associated with higher risk for the combined endpoint of mortality and heart failure hospitalization (hazard ratio: 2.51; 95% confidence interval: 1.24–5.1; P = 0.01), whereas iron deficiency showed a trend towards more heart failure hospitalizations (hazard ratio: 2.94; 95% confidence interval: 0.94–9.03; P = 0.09).

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highly significantno p-value reported

However, we extend previous data by showing a highly significant association of anaemia with heart failure hospitalization by factor 3, indicating a particular role of anaemia with progression of the cardiac disease.

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of borderline significanceno p-value reported

MitraClip Iron deficiency Anaemia Functional outcomes At baseline, PCS , MCS, MLWHFQ, and NYHA class were similar by ID status, whereas 6MWD was lower in patients with ID, which was of borderline significance ( Figure 2 A – E ).

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