In vitro nucleus pulposus tissue model with physicochemical stresses.

JOR Spine · 2020 · PMC7524234 · PMID 33015578

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showed a trendno p-value reported

Cyclic hydrostatic pressure (HP) for 4 days followed by constant HP for 3 days in high osmolality (HO; 450 mOsm/kg H 2 O) showed a trend towards upregulated aggrecan expression and dense accumulation of keratan sulfate without gaps by the NP cells.

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