Effects of a Web-Based, Evolutionary Mismatch-Framed Intervention Targeting Physical Activity and Diet: a Randomised Controlled Trial.

There was a statistically non-significant difference of small to medium effect size between groups’ 12-week change scores for total energy intake (AM∆ = − 214 kcal/day, 95% CI = − 481 to 53, d = − 0.49); the intervention group made a statistically significant reduction of large effect size in energy intake (mean (SD) 12-week change = − 431 kcal/day (694), t(28) = 3.34, p < 0.01, d = 0.81), whereas the slight decrease in energy intake found for the control group did not reach statistical significance ( p > 0.05).

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