Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.

JCI Insight · 2020 · PMC7526459 · PMID 32879135

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did not reach statistical significanceno p-value reported

reported a trend toward a decrease in Pcsk1 mRNA in the Snord116 p–/m+ hypothalamus, although this was only observed during fasting and did not reach statistical significance ( 46 ).

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