Th2-related GATA3 and Th17-related RORC were not significantly differentially expressed between uTreg and bTreg (and uTconv and bTconv), although RORC showed a trend toward downregulation, which was confirmed on the protein level ( Figure 5, A and B ).
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Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor Tregs.
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