BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer.

Statistical analysis also showed a trend towards a statistically significant association with PTEN-loss: indeed, PTEN-loss predicted an IL-8 value higher than 42.5 pg/mL with a 64.29% sensitivity and 78.57% specificity (AUC = 0.71) and the ROC curve-based prediction algorithm based on PTEN-loss had 43% accuracy in predicting IL-8 production ( p = 0.05) (Fig. 1b ).

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