Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx).

Proc Natl Acad Sci U S A · 2020 · PMC7533878 · PMID 32929035

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showed a trendno p-value reported

Strikingly, in all our heart models, the distal I-band titin region showed a trend toward increased oxidation which became significant when stretch was also included ( Figs. 1 E and 4 A ).

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