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A novel dual MEK/PDK1 inhibitor 9za retards the cell cycle at G<sub>0</sub>/G<sub>1</sub> phase and induces mitochondrial apoptosis in non-small cell lung cancer cells.

PeerJ · 2020 · PMC7537639 · PMID 33072436

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showed a trendno p-value reported
It is notable that when the concentration was less than or equal to 10 μM, 9za showed a trend of dose-dependent cell cycle arrest in G 0 /G 1 phase.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.