Preoperative serum circulating microRNAs as potential biomarkers for chronic postoperative pain after total knee replacement.

Model 2 was constructed using a backward selection of the parameters included in model 1 and identified preoperative pain intensity (P < 0.001) as a significantly independent parameter for postoperative pain relief prediction with a value of R 2 of 30% and showed a trend of hsa-miR-146a-5p (P = 0.06) ( Table 3 , model 2).

also in 53,322 other papers