Impact of age on the toxicity of immune checkpoint inhibition.

10.1136/jitc-2020-000871.supp1 Supplementary data Discussion Our study did not observe a significant difference in overall toxicity between age cohorts, although there was a numerical trend toward lower all-grade and ≥G3 toxicities in the ≥75 years compared with the younger cohort, and the discontinuation rates for toxicity were lowest in the oldest age cohort.

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There was a strong trend toward lower intravenous steroid use in the older cohorts, with more of these patients being treated with oral steroids instead.

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