Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations.

J Neuroinflammation · 2020 · PMC7547498 · PMID 33036616

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showed a trendno p-value reported

CD68 expression was downregulated in microglia following alcohol consumption, while the remainder of the activation markers were not significantly altered, although both CD86 and CD163 showed a trend toward increased expression in alcohol-fed mice.

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a decreasing trendno p-value reported

an increasing trendno p-value reported

The expression of these markers was not significantly changed on CNS IMs, although an increasing trend was observed for CD86 and a decreasing trend for CD163.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.