[ 69 ] observed comparable ABCB1 mRNA expression in duodenal mucosa in pediatric patients with untreated celiac disease in comparison with healthy controls, with an increasing trend in the disease progression.
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The sentences
An animal model of chronic inflammation produced by exposure to Mycobacterium butyricum suggest that mdr1a mRNA expression in intestinal tissues was not significantly changed (may be due to a high variability of the results), but a strong trend towards downregulation was seen [ 52 ].