Clinical Evidence of Antidepressant Effects of Insulin and Anti-Hyperglycemic Agents and Implications for the Pathophysiology of Depression-A Literature Review.

Int J Mol Sci · 2020 · PMC7554794 · PMID 32971941

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0880

boldest claim

The sentences

borderline significantp = 0.056so close (0.05 < p ≤ 0.1)

However, there was a borderline significant difference between the two groups ( p = 0.056) in the IDS-C30 score favoring the placebo.

also in 11,409 other papers

near-significantp = 0.088so close (0.05 < p ≤ 0.1)

[ 44 ] reported no correlation between changes from baseline in HDRS scores and in HOMA-IR values, but also reported that greater changes in HOMA-IR values predicted greater reduction in HDRS scores, with a near-significant p -value ( p = 0.088).

also in 2,306 other papers

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