Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency.

Consistent with these findings, urinary excretion of gentamicin was higher in the group treated with cilastatin than in that treated with gentamicin alone, although the difference did not reach statistical significance ( Figure 11 F).

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