A recent review showed a trend toward higher rates of grade 3+ pneumonitis after reirradiation with SBRT when starting with an initial conventionally fractionated RT course. 2 , 9 , 12 The question remains if there is recovery of lung parenchyma over time, which allows for improved tolerance for reirradiation.
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Repeat Thoracic Stereotactic Body Radiation Therapy (SBRT) for Nonsmall Cell Lung Cancer: Long-Term Outcomes, Toxicity, and Dosimetric Considerations.
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