IMVAMUNE^® and ACAM2000^® Provide Different Protection against Disease When Administered Postexposure in an Intranasal Monkeypox Challenge Prairie Dog Model.

For animals vaccinated on Day 3 postexposure ( Figure 4 D), ACAM2000 ® -vaccinated—but not IMVAMUNE ® -vaccinated—animals’ lesion counts were lower than unvaccinated animals at all time-points, but this difference did not reach statistical significance by two-way ANOVA ( p < 0.05). 3.5.

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