Onion Bulb Extract Downregulates EGFR/ERK1/2/AKT Signaling Pathway and Synergizes With Steroids to Inhibit Allergic Inflammation.

Furthermore, while treatment with either OBE at 30 mg/kg or dexamethasone at 0.5 mg/kg alone reduced the eosinophil influx, this did not reach statistical significance (OBE 30 and 0.5 mg/kg dexamethasone alone vs HDM, 1.9 ± 0.3 and 1.3 ± 0.1 vs 3.7 ± 0.3 × 10 5 , respectively, P > 0.05; Figure 9B ).

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