The healthy exocrine pancreas contains preproinsulin-specific CD8 T cells that attack islets in type 1 diabetes.

Sci Adv · 2020 · PMC7567597 · PMID 33067232

Europe PMC DOI

hedged sentence

0.0564

closest p · 1.1× alpha

0.0564

boldest claim

The sentences

a strong trendP = 0.0564so close (0.05 < p ≤ 0.1)

In addition, there was a strong trend in increased PPI-specific CD8 + T cells in exocrine regions comparing donors with T1D to healthy controls ( P = 0.0564; Fig. 1B ), and compared to previously reported frequencies ( 13 ) of such autoreactive CD8 cells in blood, this constituted a substantial enrichment.

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