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Tubular Secretion Markers, Glomerular Filtration Rate, Effective Renal Plasma Flow, and Filtration Fraction in Healthy Adolescents.

Kidney Med · 2020 · PMC7568071 · PMID 33089146

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Other groups demonstrated that lower tubule secretion of these compounds was associated with higher mortality risk and suggested a higher risk for chronic kidney disease progression; however, the latter finding did not reach statistical significance. 3 These secreted molecules included compounds structurally similar to PAH.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.