Barely Significant
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A real-world study of the dosing and tolerability of pirfenidone and its effect on survival in idiopathic pulmonary fibrosis.

Sarcoidosis Vasc Diffuse Lung Dis · 2020 · PMC7569556 · PMID 33093778

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showed a trendno p-value reported
In case, a patient does not opt for or tolerate nintedanib, one can still administer a lower dose of pirfenidone as the survival in the reduced-dose group also showed a trend towards improvement in our study (though statistically non-significant).

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