Efficacy and safety of exogenous surfactant therapy in patients under 12 months of age invasively ventilated for severe bronchiolitis (SURFABRON): protocol for a multicentre, randomised, double-blind, controlled, non-profit trial.

BMJ Open · 2020 · PMC7574934 · PMID 33077567

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a marked trendno p-value reported

22 Interestingly, outcomes including the PICU LOS, PO 2 /FiO 2 and CO 2 elimination were better in patients treated with surfactant, with a marked trend toward less duration of mechanical ventilation.

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