Immune infiltration and immune gene signature predict the response to fluoropyrimidine-based chemotherapy in colorectal cancer patients.

Oncoimmunology · 2020 · PMC7575007 · PMID 33117604

Europe PMC DOI

hedged sentences

0.0180

closest p · 0.4× alpha

0.0570

boldest claim

The sentences

marginally significantp = .018actually significant

Patients with high risk had shorter RFS in the validation set1 with a marginally significant p -value of 0.069 Figure 4f and shorter OS ( p = .018, Figure 4g ).

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marginal significancep = .057so close (0.05 < p ≤ 0.1)

The Imm-R model could also distinguish high-risk patients who received FOLFOX treatment but only with marginal significance ( p = .057, Figure 5e ).

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showed a trendno p-value reported

The Imm-R scores (upper panel) and corresponded OS (middle panel) of individuals in training set ( Figure 4m ) and validation set2 ( Figure 4n ) showed a trend that the OS roughly decreased along with the increasing of Imm-R scores.

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