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GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal subtype.

Sci Rep · 2020 · PMC7576136 · PMID 33082481

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closest p · 1.4× alpha
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showed a trendP = 0.069so close (0.05 < p ≤ 0.1)
Moreover, the IPMN cases with intestinal subtype showed a trend of higher values of GNAS mutant allele frequencies in their cfDNA than those with other subtypes ( P = 0.069, Fig. 4 ).

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