Functional annotation of each of the three neuroticism factors was carried out in FUMA ( http://fuma.ctglab.nl/ ) using all SNPs found within the independent genomic loci that were in LD of r 2 ≥ 0.6, were nominally significant, and had a MAF of ≥0.0005.
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Genetic contributions to two special factors of neuroticism are associated with affluence, higher intelligence, better health, and longer life.
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