Epigenetic clocks may come out of rhythm-implications for the estimation of chronological age in forensic casework.

In contrast, samples from individuals with low physical activity (low score on International Physical Activity Questionnaire, LASA Physical Activity questionnaire, low Cambridge Physical Activity Index, sedentary job and no recreational activity or < 1 h/week of physical activity) showed a trend towards a slight increase in epigenetic age estimation [ 27 ].

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