Compared to the rest of the UK, the six sites based in London were slower to open (median of 242 days) and to recruit the first patient (median of 150 days) although this did not reach statistical significance ( p values of 0.21 and 0.07, respectively, using the log rank test).
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Letter on Predicting the number of sites needed to deliver a multicentre clinical trial within a limited time frame in the UK.
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