Upregulation of the heterogeneous nuclear ribonucleoprotein hnRNPA1 is an independent predictor of early biochemical recurrence in TMPRSS2:ERG fusion-negative prostate cancers.

It showed that most of these associations were driven by the subset of ERG-negative cancers (Supplementary Table 1 ) but failed to reach statistical significance in ERG-positive cancers (Supplementary Table 2 ). hnRNPA1 and genomic deletions Most chromosomal deletions in prostate cancer are linked either to cancers harboring ERG fusions (3p, 8p, PTEN, 12q, 16q, 17p) [ 21 , 24 , 25 , 28 , 29 , 49 ] or to the ERG-negative subset (5q, 6q, 13q, 18q) [ 6 , 20 , 23 , 26 ].

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