Treatment with Mammalian Ste-20-like Kinase 1/2 (MST1/2) Inhibitor XMU-MP-1 Improves Glucose Tolerance in Streptozotocin-Induced Diabetes Mice.

However, we observed a slight trend of increasing cell survival against STZ-induced toxicity when XMU-MP-1 was added at a lower dose (1 μM).

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We observed more cell survival following treatment with 1 μM XMU-MP-1 on INS-1 treated with 1 mM STZ ( Figure 2 B) and in cells treated with 2 mM STZ ( Figure 2 C), although the differences did not reach statistical significance. 2.3.

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