Identifying genetic factors that contribute to the increased risk of congenital heart defects in infants with Down syndrome.

Sci Rep · 2020 · PMC7582922 · PMID 33093519

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nominally significantno p-value reported

In our analyses, NOTCH4 and CEP290 , whose roles in heart development and the ciliome have been previously described 36 , 37 , were found to have nominally significant associations with DS + AVSD in both WES and WGS datasets.

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