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Misfolding of Lysosomal α-Galactosidase a in a Fly Model and Its Alleviation by the Pharmacological Chaperone Migalastat.

Int J Mol Sci · 2020 · PMC7583893 · PMID 33036426

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There was a slight change in the climbing ability of flies expressing the A285D mutation at day 15 post-eclosion; however, it did not reach statistical significance and was not recapitulated at day 22 post-eclosion. 2.4.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.