However, mean PaO 2 /FiO 2 (223 ± 73 mmHg vs 203 ± 110 mmHg, p = 0.69), oxygen saturation (87 ± 18 vs 82 ± 9%, p = 0.19), pH (7.25 ± 0.2 vs 7.11 ± 0.1, p = 0.15) and heart rate (117 ± 29 vs 161 ± 16 beats/min, p = 0.06) showed a trend towards physiologic benefit of the treated animals compared to controls (Fig. 3 ).
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Veno-venous ECMO as a platform to evaluate lung lavage and surfactant replacement therapy in an animal model of severe ARDS.
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