The number of cells that stained for ALDH1, but not CGA, showed a trend in the opposite direction with proportions being, respectively, 19%, 22%, 72%, and 81%.
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APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development.
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