Anemarsaponin BII inhibits the activity of CYP3A4, 2D6, and 2E1 with human liver microsomes.

Pharm Biol · 2020 · PMC7592892 · PMID 33103940

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clearly significantno p-value reported

Results Effect of anemarsaponin BII on the activity of CYP450s Compared with untreated HLMs, the pre-treatment of positive inhibitors had a clearly significant effect on the activity of all CYP isoforms, and only the activity of CYP3A4, 2D6 and 2E1 was significantly inhibited by anemarsaponin BII.

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