showed a trendP = .091
According to classification of AKIP1 low/high+/high++/high+++ expression, increased grade of AKIP1 expression was correlated with larger tumor size ( P = .003), extrathyroidal invasion ( P < .001), higher pT stage ( P < .001), and it showed a trend to be positively correlated with pN stage ( P = .091) as well as pTNM stage ( P = .060) (but without statistical significance), while it was not correlated with age ( P = .437) or gender ( P = .492). 3.4.