Image Quality and Interpretation of [¹⁸F]-FES-PET: Is There any Effect of Food Intake?

An inverse relationship regarding physiological [ 18 F]-FES uptake was seen for the small bowel, with the lowest median tracer uptake in the fasting group (1.9 (1.3–6.1)) and highest for the chocolate group (5.5 (1.5–10.8); p = 0.17; Table 2 and Figure 4 )), although the effect of food intake did not reach statistical significance yet.

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A previous case report presented [ 18 F]-FES-PET findings of a patient with metastatic lobular BC with gastric linitis plastic [ 20 ], in which the chocolate protocol may possibly have facilitated tumor detection because of a nonsignificant trend towards lower uptake in the stomach wall.

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