Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models.

Cancers (Basel) · 2020 · PMC7602510 · PMID 33066609

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showed a trendno p-value reported

Ki-67 staining showed a trend towards reduced cell proliferation in the high BCL-2 expressing CRC0076 PDXs upon ABT-199 treatment.

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a numerical trendno p-value reported

Our data suggest a numerical trend towards decreased cell proliferation (Ki-67 staining) in CRC0076 (which expresses high levels of BCL-2) following ABT-199 treatment ( Figure S5 ). 2.3.

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